Treatment of primary focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis is scar tissue in the filtering unit of the kidney. This structure is called the glomerulus. The glomeruli serve as filters that help the body get rid of harmful substances. Each kidney has thousands of glomeruli.

Primary FSGS can present acutely with overt nephrotic syndrome characterized by hypoalbuminemia and edema. However, primary FSGS can also present insidiously with less dramatic manifestations, possibly related to the underlying histologic variant. The diagnosis of primary FSGS is confirmed by a renal biopsy that reveals the morphologic features mentioned above plus diffuse (greater than 80 percent) effacement of the foot processes by electron microscopy.

The condition affects both children and adults. It occurs slightly more often in men and boys. It is also more common in African Americans. Focal segmental glomerulosclerosis causes up to a quarter of all cases of nephrotic syndrome.

What are the symptoms

FSGS can also cause abnormal results in two different routine laboratory tests ordered by your doctor.  The first is a test of kidney function called “creatinine." It is measured by taking a blood sample.  Everyone has a certain amount of a substance called creatinine floating in his or her blood.  This substance is always being produced by healthy muscles, but since the kidneys constantly filter it out the level of creatinine stays low.  When the filters become damaged, the level of creatinine left in the blood goes up.  A higher level of creatinine alerts the doctor that the kidneys aren’t filtering as well as they should.

The second test is for protein in your urine.  Urine normally contains only a very small amount of protein.  It is just too big to pass through the filters.  But when the filters become scarred or damaged, they can “leak” protein into the urine.  If a doctor finds too much protein in your urine, it usually means something is wrong with the filters.  Some people with a large amount of protein in their urine say that their urine looks “foamy”, like bubbles built up in dishwater.

None of the above symptoms, or even all of them together, is specific for FSGS.  If you or your doctor are concerned about FSGS, the only way to know for sure is to have a kidney biopsy.

Traditional Chinese Treatment

However, healthy life and control complications do nothing to the damaged glomeruli. Here, Micro-Chinese Medicine Osmotherapy can be a good choice. As a combination of TCM and modern technology, it can not only relive the symptoms but also restore kidney function. For detailed information, you can send us email:kidneyhospitalabroad@hotmail.com and we are glad to help.

What Factors Can Lead to Swelling for FSGS Patients?

Swelling is the common symptom of FSGS, it really influence the life quality of patients a lot. How to manage it is the important for patients. Now, the proper factors are listed, and patients can have a good prevention and control through eliminate these factors.

1. Water and sodium retention

As we all know, kidneys are able to excrete excessive water and sodium from your body to keep them in a balanced state. However, when you are diagnosed with FSGS, your kidneys fail to remove excessive water or fluid our of your body. In this condition, water retention will present in your body. Excessive water in your body will move to the tissue space which contributes to swelling in your body. Besides, if you intake much sodium which can absorb water, you will also have swelling. Sodium intake means that you absorb excessive water again. In this way, sodium intake will worsen your swelling and burden your kidneys.

2. Heavy loss of protein

In normal case, protein is in blood as a solute, which is used to maintain the balance inside and outside the blood vessels. However, due to FSGS, lots of protein leaks into urine. As a result, osmotic pressure in blood vessels is changed. In order to keep balance, fluid oozes into surrounding tissues which causes swelling or edema.

Water or sodium retention and heavy loss of protein both contribute to swelling of FSGS patients. Knowing what causes their swelling, they can take effective treatment to control swelling so as to delay the progression of FSGS into renal failure. In their daily diet, they can choose some foods which are low sodium and avoid some high sodium foods such as pickles, bacon and processed foods. And limiting water intake is also helpful.

Diet changes can not treat swelling radically and they should treat this symptoms from root. That is to say, they should repair their injured kidney inherent cells and improve kidney function.


Do you have any other questions about eliminate swelling in FSGS, you can contact our online doctors, leave us messages or send email to kidneyhospitalabroad@hotmail.com, we will reply you within 24 hours.

Proper Diet for FSGS Pateints

FSGS is the common kidney damage and one of leading cause of kidney function decline. Kidneys are the main metabolism organs, with the metabolic disorder, patients suffer more and more complications and symptoms. To live a high quality and long life, diet should be cautious. Here list some diet suggestions which can help FSGS patients a lot.

1.Keep enough vitamin intake

Vitamins are necessary for people especially for children, because keeping enough vitamin intake can improve the immune system which will make children get rid of cold and infection. And cold and infections are the common reasons for the deterioration of FSGS. Fruits and vegetables are high in vitamins, and different fruits and vegetables contain different vitamins, in order to keep the balance of the vitamins in body, they need to keep enough fruits and vegetables intake depending on their illness condition.

2. Keep enough protein intake

Protein urine is a common symptom for FSGS patients, they should keep proper protein intake in order to reduce the further kidney burden. However, protein is a necessary nutrition for children with their growth on both physical and mental. So children with FSGS should keep enough protein intake everyday, and the amount is different from their illness condition. Besides, they should take high protein foods such as fish, lean meat, egg whites and milk.

3. Keep enough calcium intake

Calcium is important for the development of children, and tacking enough calcium is helpful to strong their bones. And for FSGS children who have high phosphorus level, they need to eat more high-calcium foods, such as cheese, sesame seeds and yogurt. If it is necessary, they can take some calcium medicines.

Above are just some systematic diet suggestions. The detailed diet plan should be set up according to the every patients’ practical disease condition. If you need any our help, you can send an email to the experts online, leave us messages or send email to kidneyhospitalabroad@hotmail.com, our experts will reply you as soon as possible.

Gout in FSGS: Cause and Treatment

Can gout be caused by FSGS? In fact, some FSGS patients are bothered by gout which can cause horrible pain in joints and make patients sicker and sicker. The sever pains patients suffer from gout also urge them to know the cause and treatment for FSGS.

How does FSGS cause gout?

As we know, kidneys have the function of filtering wastes and toxins in blood, which can keep the balance of the internal environment of body. However, once the kidneys are damaged, they will fail to work well. And the wastes will build up in body, such as creatinine, BUN and uric acids. The accumulation of uric acids in blood will cause gout, and some certain medications for FSGS such as water pills will also cause the increase of the uric acid levels.

How to treat the gout of FSGS patients?

Here are some common medications for FSGS patients to relieve their gout, such as prednisone, allopurinol and colchicine. These medications will be helpful in remitting the gout and joint pain.

Prednisone is used commonly in treating the gout for FSGS patients, and prednisone is often taken with food, which will prevent the stomach upset. It can also prevent the acute gout attack, but the long-term use of prednisone will case some side effects.

Allopurinol is usually used to prevent the gout attacks, and help patients who experience gout frequently. And the allopurinol should be taken everyday, which can help reduce the uric acids in blood.

Colchicine is often used when people experience gout attack in the first time, which is effective in relieving the gout. And the doctor will help patients to follow a certain dosage based on their kidney function and side effects.


Of cause, the root treatment for gout should be reversing kidney functions to decreased the uric-acid level. traditional Chinese medicine is the good for remitting symptoms and reversing kidney functions. If you want to know more information about this therapy for FSGS, you can send an email to the experts: kidneyhospitalabroad@hotmail.com, or contact our online doctors, we will reply you within 24 hours.

The Obvious Symptoms of FSGS

FSGS has become one of leading causes of renal failure, but FSGS is the chronic disease, with the timely and effective prevention and treatment in the early stage of the disease, patients also can live a high quality life like common people. Now the obvious symptoms of FSGS are recommended, patients should have a close monitor about their physical conditions and remitting these symptoms to protect kidney functions.

The obvious symptoms of FSGS include:

1. Swelling

In general, swelling firstly occurs in eyelid, face and lower limbs. Without effective control, it may spread to the whole body. Fluid limitation is needed when swelling appears and how much water is needed depends on patients’ specific illness condition.

2. Blood urine

Blood urine appears when excess red blood cells leak into urine from kidney. In normal condition, blood flow into kidney and during this process, wastes and nutrition are separate. However, for FSGS patients, their glomeruli have been injured. Damaged glomerular filtration membrane fails to function properly. Under such a condition, red blood cells leak into urine, causing blood urine.

3. Foamy urine

Foamy urine is the clinical manifestation of proteinuria; and for patients who are experiencing foamy urine associated FSGS, they need to adjust their protein intake, so as to avoid increasing kidney burden. Besides, about 60% of the protein ingested by them should be high quality protein which can be found in fish, lean meat, egg white and milk.

4. Tiredness

This symptom becomes especially serious with the progression of illness. For FSGS patients, tiredness or fatigue occurs easily when renal anemia is caused. Therefore, preventing renal anemia is very important for preventing tiredness.

5. Dizziness

FSGS patients may also feel dizziness when their blood pressure is elevated. High blood pressure refers to the high impact of blood on blood vessels. It can be caused by kidney disease, including FSGS, directly. Although high blood pressure occurs as a symptom of FSGS in many cases, if not treated well, it will accelerate FSGS to kidney failure stage. Therefore, if FSGS patients feel dizzy, they should be alert about their blood pressure.


If you have some of the above symptoms, you should see a doctor as soon as possible. And if you have any other questions about FSGS symptoms or treatment, you can contact our online doctors, leave us messages or send email to kidneyhospiatalabroad@hotmail.com, we will reply you within 24 hours.