The Common Cause of FSGS

What are the common causes of FSGS? This is question that all of patients want to care most. This article will focus on this.

Focal Segmental Glomerulonephritis (FSGS) is a renal disorder, in which scar tissue covers some sections of glomeruli. These scars can damage glomerular basement membrane and lead to nephrotic syndrome, Chronic renal failure and uremia. FSGS causes can be divided into two broad categories, primary and secondary. Here, we mainly talk about the secondary causes.

Primary causes of FSGS

Primary causes of FSGS means that doctors have not found its underlying causes. Usually, it presents as nephrotic syndrome. However, there are several currently genetic reasons which are associated with FSGS.

Secondary cause of FSGS

Secondary cause of FSGS means that it is associated with the other disorders.
1. Infections, including HIV, Hepatitis B and Parvovirus.

2. Diseases, such as massive obesity, sickle cell nephropathy and congenital cyanotic heart disease.

3. The damage to glomeruli. There are thousands of tiny filters in kidneys, called glomeruli, which overworks to push their limits by other diseases.

No matter primary or secondary FSGS causes, it is sure that FSGS results from the damage of glomerular basement membrane. What we can do is to repair the impaired glomeruli, thus avoids or delay the progress of FSGS (Focal Segmental Glomerulonephrits).


If you want to know more details about the causes of FSGS, you can send email to kidneyhospitalabroad@hotmail.com.