Diabetes and Chronic Kidney Disease

what is the relationship of Diabetes and Chronic Kidney Disease?

Kidney disease is common among patients with Type 2 diabetes and hypertension. It is characterized by a persistent and usually progressive decline in renal function as measured by glomerular filtration rate and/or albuminuria. Given the rise in the incidence of obesity, Type 2 diabetes and hypertension, the associated incidence of diabetic nephropathy has reached epidemic proportions in industrialized nations. Treatment of patients with diabetic nephropathy (DN) includes treatment of the underlying Type 2 diabetes and hypertension. Angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are commonly prescribed to control hypertension and slow the progression of DN. Nevertheless, about 20% of patients eventually progress to end-stage renal disease (ESRD) and require hemodialysis, peritoneal dialysis, or renal transplant. Therefore, we believe an unmet medical need for safe and convenient treatments to retard or reverse the progression of DN persists.

Diabetic Nephropathy is a kind of Kidney disease from long-standing diabetes. Diabetes affects the tiny blood vessels in the glomerulus, a key structure in the kidney composed of capillary blood vessels. This structure is critical for blood filtration. Features of diabetic nephropathy include nephrotic syndrome, which is characterized by excessive protein in the urine, high blood pressure, and progressively impaired kidney function. With severe diabetic nephropathy, kidney failure, end-stage renal disease requiring kidney dialysis or a kidney transplant may result. Also known as intercapillary glomerulonephritis, Kimmelstiel-Wilson disease, and Kimmelstiel-Wilson syndrome.


Diabetes can progress into Chronic Kidney Disease for a few years, if you happen to have Diabetes, you should seek for proper treatment to treat it. If you can treat it in the best opportunity, there will be difficult to treat it in advanced stage.