2014年10月30日星期四

The Latest Treatment for IgA Nephropathy with High Creatinne Level

IgA Nephropathy is a kind of immune disorder, which causes patients to worry about the problem that is there any treatment can help them to treat IgA Nephroapthy?

IgA nephropathy, also called Berger’s Disease, is an auto-immune disease. It usually happens some time after patients catch cold or get infected. And studies suggest that it occurs due to immune disorder. Finding proper treatment to prevent and treat the disease attracts most patient and their family’s attention. And TCM is said to be effective in treating this disease. Here we will explain how does TCM work in IgA nephropathy-autoimmune disease.
First, prevent and reduce the possibility of IgA nephropathy, improve patient’s resistance.

Effective substances can improve patient’s resistance, prevent and reduce the possibility of IgA nephropathy through the following three aspects:
1. The effective substances can increase the lysosome level by improving lymphocytes’ transformation rate and absorption of IL-2; Increase the activity of patient’s natural killer cells; Improve patient’s cellular immunity; Improve antibody’s lethality to pathogens, duly protecting patient’s kidney from immune damage.
2. It can activate generation of IgG and IgM in patient’s body, improve synthesization of IgM and IgG antibody, strengthening patient’s humoral immunity; inhibit generation of abnormal IgA antibody, duly reducing and blocking the immune damage to kidneys due to immune responses induced by abnormal IgA antibody.

3. It can also improve IgA nephropathy patient’s non specific resistance by activating phagocyte’s phagocytosis in patient’s body, speed up phagocytosis of immune complex, duly laying solid foundation for repairing the damaged IgA nephropathy patient’s kidney cells.

Second, it can inhibit further kidney damage by immune responses; the effective substances, after entering into patient’s body, controls proteinuria resulting from immune responses through the following four aspects:

1. The effective substances, after entering patient’s body, first activate the NOS of glomerular endothelial cells, speed up generation of NO, as well as the GC-PK, duly recovering the function of damaged endothelial cell in glomerular capillaries; Inhibit synthesization and secretion of ET-1, further improving the micro-circulation inside the glomeruli, dilating blood vessels, stabilizing blood pressure, increasing blood and oxygen supply, which provides good environment for repairing the damaged kidneys.

2. The effective substances, by improving ischemia and anoxia inside the kidneys, further prevent further damage to endothelial cells in capillaries; inhibit more synthesization of inflammatory factors, cell factors, growth factors, etc. At the same time, it can also inactivate the toxicity; improve absorption of IL-2, prevent IL-2 from further damaging charge barrier, duly reducing proteinuria.

3. It can also recover endothelial cells’ anti-coagulation function resulting from inflammatory responses by inhibiting activation of platelet function. As far as platelet’s coagulation function is not activated, platelet can not be able to secrete clotting factors like PDGF, TXA2, 5-HT, platelet IV factors, ADP, etc. So, there will not be micro-thrombus, and blood circulation inside glomeruli will not be blocked, and there will not be proteinuria.

4. At the same time, the effective substances can also inhibit inflammation induced by immune complex, which further reduce the generation of free radical, duly prevent lipid peroxidation;

Third, the effective substances can block renal fibrosis, relieving and delaying renal damage. As above mentioned that the effective substances can dilate blood vessels, improve blood circulation inside the kidneys, fight against coagulation and inflammation, degrade extracellular matrix, duly recovering the normal function of damaged kidney functional cells and improving kidney function.


The natural treatments for treating IgA Nephroapthy have been listed, if you want to know more, you can send email to kidneyhospitalabroad@hotmail.com.

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